(R)-1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID - Names and Identifiers
Name | 1,3-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl)easter, (R)
|
Synonyms | C67151 (R)-N-Cbz-3-pyrrolidinecarboxylic Acid (R )-1-Cbz-pyrrolidine-3-carboxylic acid (R)-1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID (3R)-1-benzyloxycarbonylpyrrolidine-3-carboxylic acid (R)-1,3-PYRROLIDINEDICARBOXYLIC ACID, 1-(PHENYLMETHYL)EASTER 1,3-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl)easter, (R) 1,3-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (3R)-
|
CAS | 192214-06-5
|
InChI | InChI=1/C13H15NO4/c15-12(16)11-6-7-14(8-11)13(17)18-9-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H,15,16)/t11-/m1/s1 |
(R)-1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID - Physico-chemical Properties
Molecular Formula | C13H15NO4
|
Molar Mass | 249.26 |
Density | 1.309g/cm3 |
Boling Point | 432.3°C at 760 mmHg |
Flash Point | 215.3°C |
Vapor Presure | 3.06E-08mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.582 |
(R)-1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID - Introduction
1, + acid, 1-(phenylmethyl)easter, (R) is an organic compound whose structure contains a pyrrole ring and a formic acid group. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1, sulfuric acid, 1-(phylmethyl) easter, (R) is a solid with a white crystalline appearance. Its molecular formula is C16H15NO2 and its molecular weight is 253.30g/mol. The compound is insoluble in water at normal temperature, but is soluble in some organic solvents such as ethanol, acetone and dimethyl sulfoxide.
Use:
1, sulfuric acid, 1-(phenmethyl) easter, (R) is a commonly used organic synthesis intermediate. It can be used to prepare biologically active compounds and is often used to synthesize multiple drug molecules in the field of drug development. In addition, it can also be used as a catalyst and a chiral separating agent in organic synthesis reactions.
Method:
The preparation of
1, 1-acid, 1-(phenmethyl) easter, (R) usually uses 1-ethanol and chloroformic acid chloride methyl ester. First, 1-pyrroleethanol and chloromethyl chloroformate were subjected to condensation reaction under alkaline conditions to yield 1, + acid, 1-(phenylmethyl)easter, (R) chloromethyl ester. Next, chloromethylchloroformate is treated with alkali to yield 1-acid, 1-(phenylmethyl)easter, (R).
Safety Information:
1. acid, 1-(phenmethyl) easter, (R) is a relatively safe compound under the correct operating conditions. However, it may be irritating to the skin, eyes and respiratory tract, so care should be taken to avoid direct contact during operation. At the same time, you should operate in a well-ventilated area and wear appropriate protective equipment, such as gloves and goggles, to ensure personal safety. Proper laboratory practices and safe practices should be followed when using or handling the compound.
Last Update:2024-04-09 21:11:58